Comparison of fixed-dose weight-adjusted unfractionated heparin and low-molecular-weight heparin for acute treatment of venous thromboembolism
نویسندگان
چکیده
منابع مشابه
Comparison of fixed-dose weight-adjusted unfractionated heparin and low-molecular-weight heparin for acute treatment of venous thromboembolism.
CONTEXT When unfractionated heparin is used to treat acute venous thromboembolism, it is usually administered by intravenous infusion with coagulation monitoring, which requires hospitalization. However, subcutaneous administration of fixed-dose, weight-adjusted, unfractionated heparin may be suitable for inpatient and outpatient treatment of venous thromboembolism. OBJECTIVE To determine if ...
متن کاملFixed dose subcutaneous low molecular weight heparins versus adjusted dose unfractionated heparin for venous thromboembolism.
BACKGROUND Low molecular weight heparins (LMWHs) have been shown to be effective and safe in preventing venous thromboembolism (VTE). They may also be effective for the initial treatment of VTE. This is an update of a Cochrane review first published in 1999 and previously updated in 2004. OBJECTIVES To determine the effect of LMWH compared with unfractionated heparin (UFH) for the initial tre...
متن کاملLow molecular weight heparin versus unfractionated heparin in the initial treatment of venous thromboembolism.
In this review, we analyze data from randomized trials in which low molecular weight heparin was compared with unfractionated heparin, both to estimate the treatment effect of low molecular weight heparin in the initial treatment of venous thromboembolism and to evaluate the effect of the varied proportion of included cancer patients (6% to 22.7%) on the incidence of outcome events (recurrence ...
متن کاملReview: low-molecular-weight heparin reduces recurrent venous thromboembolism better than unfractionated heparin.
and commentary also appear in ACP Journal Club. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . For correspondence: Professor M Prins, University of Maastricht, Maastricht, The Netherlands. [email protected] Source of funding: Scottish Executive UK. Commentary P revious meta-analyses comparing fixed dose LMWH with ...
متن کاملUnfractionated and low molecular weight heparin
Background Unfractionated heparin (UFH) is mostly obtained from porcine and bovine mucosa and has been widely used for the treatment and prevention of thrombotic events. It consists of molecular chains of various lengths varying from 2000 to 40,000 Da [1]. Low molecular weight heparins (LMWHs) are smaller chains of UFH that can be obtained, from unfractionated heparin, by various chemical and e...
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ژورنال
عنوان ژورنال: Journal of Vascular Surgery
سال: 2007
ISSN: 0741-5214
DOI: 10.1016/j.jvs.2006.11.003